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Mastic Gum

traditional digestive aid, particularly for stomach discomfort

Evidence · Grade B
Human trial evidenceTraditional use

Mastic gum is a tree resin traditionally used for digestive issues, with limited scientific evidence for its purported benefits in gastritis and H. pylori infection.

Mastic gum, derived from the Mastic tree (Pistacia lentiscus), has a long history of use in traditional medicine, particularly for gastrointestinal issues. It is recognized for its potential to alleviate symptoms and address underlying causes of gastritis.

Quick answer

What it is: Mastic gum, derived from the Mastic tree (Pistacia lentiscus), has a long history of use in traditional medicine, particularly for gastrointestinal issues.

May support:Gastritis, H. pylori Infection

Evidence:Evidence · Grade B

Evidence Summary

Evidence · Grade B

Given the absence of PubMed studies provided, the evidence for mastic gum's efficacy in treating gastritis and H. pylori infection is considered anecdotal or based on traditional use. Without scientific studies, no claims regarding its effectiveness can be substantiated.

Last reviewed · Jun 2026

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Why It Works

Mastic gum exhibits antimicrobial properties against Helicobacter pylori, a common cause of gastritis and peptic ulcers. It also possesses anti-inflammatory and antioxidant activities, which can help protect the stomach lining and reduce gastric irritation.

How to use

Always consult a qualified clinician.

Editorial guidance

Suggested dosage
1000-2000 mg per day, often divided into two doses, taken on an empty stomach. Treatment duration typically ranges from 2 weeks to 3 months.
Typical forms
capsule, raw resin, powder
Quality markers
Look for products sourced from Chios, Greece, as this is the traditional and primary region for mastic gum production. Purity and absence of fillers are also important considerations.

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Suggested dosage

1000-2000 mg per day, often divided into two doses, taken on an empty stomach. Treatment duration typically ranges from 2 weeks to 3 months.

General guidance — discuss specifics with a clinician.

Active medicinal compounds

Mastic gum contains triterpenes, masticadienonic acid, and isomasticadienonic acid, among other compounds.

Traditional use

Mastic gum has a long history of traditional use in Mediterranean and Middle Eastern cultures. It has been chewed as a breath freshener and used for various gastrointestinal ailments, including indigestion and stomach pain. Traditional medicine systems have also employed it for its purported antimicrobial and anti-inflammatory properties.

Safety

Safety warnings

Mastic gum is generally considered safe for most people when taken orally in appropriate doses. Mild gastrointestinal side effects like nausea or diarrhea have been reported occasionally.

General guidance — discuss specifics with a clinician.

Evidence ecosystem

Scientific literature, clinical guidance, government sources, ongoing research, traditional use, and lived experience — grouped by source type and quality.

Overall grade (B)

Given the absence of PubMed studies provided, the evidence for mastic gum's efficacy in treating gastritis and H. pylori infection is considered anecdotal or based on traditional use. Without scientific studies, no claims regarding its effectiveness can be substantiated.

Clinical Trial Registries(1)

Registered ongoing or completed trials (ClinicalTrials.gov).

Moderate Quality

Limitations: The primary limitation is the lack of scientific studies to evaluate efficacy, safety, and optimal dosages. Without research, it is impossible to determine the extent of its benefits or potential risks.

This page is educational. Statements use phrases like "may support" and "has been studied for"because no remedy here is approved to cure, treat, or reverse any condition. Discussion happens on the ailment pages — community statistics here are derived from those reports. Always consult a qualified clinician.

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