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Female Hormone Balance Protocol
For PCOS
Cycle, ovulation, and hormone metabolism support
Community score: 0.0Evidence score: 0.0
Protocol remedies
- Dose: 20 mgFrequency: once dailyTiming: morning
- D-Chiro-InositolcoreDose: 50 mg (paired with 2,000 mg myo-inositol)Frequency: Twice dailyTiming: With foodRatio: 40:1 myo-inositol to D-chiro-inositol — the physiologic plasma ratio shown to restore ovulation and improve insulin sensitivity in PCOS.
⚠ D-chiro alone or at higher DCI doses can worsen oocyte quality (the "DCI paradox"). Keep ratio near 40:1.
Meta-analysisUnfer et al. 2017 — Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trialsRCTNordio & Proietti 2012 — The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOSSystematic reviewFacchinetti et al. 2020 — Results from the International Consensus Conference on Myo-inositol and D-chiro-inositol in Obstetrics and Gynecology - Myo-InositolcoreDose: 2,000 mgFrequency: Twice dailyTiming: With foodRatio: 40:1 myo-inositol to D-chiro-inositol — pair with 50 mg D-chiro per dose.
- Magnesium GlycinatefoundationDose: 200-400 mgFrequency: once dailyTiming: with food
- Vitamin D3foundationDose: 2000-4000 IUFrequency: once dailyTiming: with a meal containing fat
- Evening Primrose OilsupportDose: 500-1000 mgFrequency: two to three times dailyTiming: with meals
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