Female Hormone Balance Protocol

Protocol remedies

• Vitex (Chaste Tree)core
  Dose: 20 mgFrequency: once dailyTiming: morning
  RCTSystematic Review of Premenstrual Syndrome and Its Treatments.
• D-Chiro-Inositolcore
  Dose: 50 mg (paired with 2,000 mg myo-inositol)Frequency: Twice dailyTiming: With foodRatio: 40:1 myo-inositol to D-chiro-inositol — the physiologic plasma ratio shown to restore ovulation and improve insulin sensitivity in PCOS.

  ⚠ D-chiro alone or at higher DCI doses can worsen oocyte quality (the "DCI paradox"). Keep ratio near 40:1.

  Meta-analysisUnfer et al. 2017 — Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trialsRCTNordio & Proietti 2012 — The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOSSystematic reviewFacchinetti et al. 2020 — Results from the International Consensus Conference on Myo-inositol and D-chiro-inositol in Obstetrics and Gynecology
• Myo-Inositolcore
  Dose: 2,000 mgFrequency: Twice dailyTiming: With foodRatio: 40:1 myo-inositol to D-chiro-inositol — pair with 50 mg D-chiro per dose.
  Meta-analysisUnfer et al. 2017 — Myo-inositol effects in women with PCOS: meta-analysis of RCTsSystematic reviewFacchinetti et al. 2020 — International Consensus on Myo & D-chiro-inositol
• Magnesium Glycinatefoundation
  Dose: 200-400 mgFrequency: once dailyTiming: with food
  Scientific reviewMagnesium intake and depression: A systematic review and meta-analysis.
• Vitamin D3foundation
  Dose: 2000-4000 IUFrequency: once dailyTiming: with a meal containing fat
  GuidelineEvaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.
• Evening Primrose Oilsupport
  Dose: 500-1000 mgFrequency: two to three times dailyTiming: with meals
  RCTThe role of essential fatty acids and prostaglandins in the premenstrual syndrome.

What People Report

Community outcomes for each remedy in this protocol for PCOS.